雅思考试时间Top↑
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具有剑桥**方教师认证资格证书，英语专业八级证书，BEC剑桥商务英语高级证书及高级英语教师资格证书。能够非常有效针对学生的短板，短时间内迅速提高学生的雅思成绩，涌现出数百位雅思听力、写作、口语高分学员（7分以上），多次创下了3到4节VIP课帮学生直接提高1.5—2分的记录。
本科一等学位毕业于英国普利茅斯大学， 研究生就读于英国萨里大学，并以优秀的成绩取的了硕士学位，现已在朗阁授教雅思和托福（主讲听力和口语），并取得5星研究员的资格，此外还有幸参与编写了冲刺阶段听力教科书。
英语听说读写学术能力过硬,拥有英语专业八级,理想的雅思考试成绩和高级英语教师资格证书，曾接受英国领事馆的雅思**方培训。从事英语教学工作已10年，有教授雅思阅读，写作和口语七年多的经验，现为广州朗阁的阅读组的组长。
雅思**方British Council认定雅思资深培训老师，从教多年，学生遍布欧美以及大洋洲各国，雅思教授课时数已经逾万。除此之外，陈老师也是RDC资深研究员，连续八次获得学术论文奖，对于雅思听力研究颇深。
成都朗阁高阶核心讲师，四川外语学院英语文学学士，英语专业八级。曾担任四川省某报刊英文编辑。从2012年起转战雅思托福教学，主讲阅读和写作；于2013参加British Council(英国教育文化协会)主办的雅思考试年度工作坊，被评为“朗阁教育集团星级研究员”。
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雅思7分铂金
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适合人群】
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词汇量6000以上，已**大学英语六级考试或雅思达到6分或同等水平。
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【课程介绍】
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课程简述：该课程适合词汇量6000以上，已**大学英语六级考试或雅思达到6分或同等水平。 教学承诺：符合学员手册所述条件，可免费重读本课程精品阶段。
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【使用教材】
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采用雅思考试出题机构剑桥大学出版“雅思预备教材”剑桥英语《ENGLISH IN MIND》及朗阁海外考试研究中心（RAFLE）内部教材
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【总课时数】
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72时
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【班级人数】
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18人
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Sleep medication linked to bizarre behaviour
12:44 06 February 2007
NewScientist.com news service
Roxanne Khamsi
New evidence has linked a commonly prescribed sleep medication with bizarre behaviours, including a case in which a woman painted her front door in her sleep.
UK and Australian health agencies have released information about 240 cases of odd occurrences, including sleepwalking, amnesia and hallucinations among people taking the drug zolpidem.
While doctors say that zolpidem can offer much-needed relief for people with sleep disorders, they caution that these newly reported cases should prompt a closer look at its possible side effects.
Zolpidem, sold under the brand names Ambien, Stilnoct and Stilnox, is widely prescribed to treat insomnia and other disorders such as sleep apnea. Various forms of the drug, made by French pharmaceutical giant Sanofi-Aventis, were prescribed 674,500 times in 2005 in the UK.
A newly published report from Australia’s Federal Health Department describes 104 cases of hallucinations and 62 cases of amnesia experienced by people taking zolpidem since marketing of the drug began there in 2000. The health department report also mentioned 16 cases of strange sleepwalking by people taking the medication.
Midnight snack
In one of these sleepwalking cases a patient woke with a paintbrush in her hand after painting the front door to her house. Another case involved a woman who gained 23 kilograms over seven months while taking zolpidem. “It was only when she was discovered in front of an open refrigerator while asleep that the problem was resolved,” according to the report.
The UK’s Medicines and Healthcare products Regulatory Agency, meanwhile, has recorded 68 cases of adverse reactions to zolpidem from 2001 to 2005.
The newly reported cases in the UK and Australia add to a growing list of bizarre sleepwalking episodes linked to the drug in other countries, including reports of people sleep-driving while on the medication. In one case, a transatlantic flight had to be diverted after a passenger caused havoc after taking zolpidem.
Hypnotic effects
There is no biological pathway that has been proven to connect zolpidem with these behaviours. The drug is a benzodiazepine-like hypnotic that promotes deep sleep by interacting with brain receptors for a chemical called gamma-aminobutyric acid. While parts of the brain become less active during deep sleep, the body can still move, making sleepwalking a possibility.
The product information for prescribers advises that psychiatric adverse effects, including hallucinations, sleepwalking and nightmares, are more likely in the elderly, and treatment should be stopped if they occur.
Patient advocacy groups say they would like government health agencies and drug companies to take a closer look at the possible risks associated with sleep medicines. They stress that strange sleepwalking and sleep-driving behaviours can have risky consequences.
“When people do something in which they’re not in full control it’s always a danger,” says Vera Sharav of the New York-based Alliance for Human Research Protection, a US network that advocates responsible and ethical medical research practices.
Tried and tested
“The more reports that come out about the potential side effects of the drug, the more research needs to be done to understand if these are real side effects,” says sleep researcher Kenneth Wright at the University of Colorado in Boulder, US.
Millions of people have taken the drug without experiencing any strange side effects, points out Richard Millman at Brown Medical School, director of the Sleep Disorders Center of Lifespan Hospitals in Providence, Rhode Island, US. He says that unlike older types of sleep medications, zolpidem does not carry as great a risk of addiction.
And Wright notes that some of the reports of “sleep-driving” linked to zolpidem can be easily explained: some patients have wrongly taken the drug right before leaving work in hopes that the medicine will kick in by the time they reach home. Doctors stress that the medication should be taken just before going to bed.
The US Food & Drug Administration says it is continuing to "actively investigate" and collect information about cases linking zolpidem to unusual side effects.
The Ambien label currently lists strange behaviour as a “special concern” for people taking the drug. “It’s a possible rare adverse event,” says Sanofi-Aventis spokesperson Melissa Feltmann, adding that the strange sleepwalking behaviours “may not necessarily be caused by the drug” but instead result from an underlying disorder. She says that “the safety profile [of zolpidem] is well established”. The drug received approval in the US in 1993.
Questions 1-6
Do the following statements agree with the information given in the reading passage?
In boxes 1-6 on your answer sheet write
TRUE if the statement is true according to the passage
FALSE if the statement is false according to the passage
T GIVEN if the information is not given in the passage
1. Ambien, Stilnoct and Stilnox are brand names of one same drug treating insomnia.
2. The woman’s obesity problem wasn’t resolved until she stopped taking zolpidem.
3. Zolpidem received approval in the UK in 2001.
4. The bizarre behaviour of a passenger after taking zolpidem resulted in the diversion of a flight bound for the other side of the Atlantic.
5. Zolpidem is the only sleep medication that doesn’t cause addiction.
6. The sleep-driving occurrence resulted from the wrong use of zolpidem by an office worker.
Question 7-9
Choose the appropriate letters A-D and Write them in boxes 7-9 on your answer sheet.
7. How many cases of bizarre behaviours are described in an official report from Australia?
A. 68
B. 104
C. 182
D. 240
8. Which of the following is T mentioned in the product information about zolpidem?
A. Treatment should be stopped if side effects occur.
B. Medication should be taken just before going to bed.
C. Adverse effects are more likely in the elderly.
D. Side effects include nightmares, hallucinations and sleepwalking.
9. Who claimed that the safety description of zolpidem was well established?
A. Kenneth Wright
B. Melissa Feltmann
C. Richard Millman
D. Vera Sharav
Questions 10-13
Answer the following questions with MORE THAN THREE WORDS each in boxes 10-13.
10. How many times was French-made zolpidem prescribed in 2005 in Britain?
11. What kind of hypnotic is zolpidem as a drug which promotes deep sleep in patients?
12. What can sleepwalking and sleep-driving behaviours cause according to patient advocacy groups?
13. What US administration says that it has been investigating the cases relating zolpidem to unusual side effects?
Answer keys and explanations:
1. True
See para.3 from the beginning: Zolpidem, sold under the brand names Ambien, Stilnoct and Stilnox, is widely prescribed to treat insomnia and other disorders such as sleep apnea.
2. False
See para.1 under the subtitle “Midnight snack”: Another case involved a woman who gained 23 kilograms over seven months while taking zolpidem. “It was only when she was discovered in front of an open refrigerator while asleep that the problem was resolved”…
3. Not Given
See para.2 under the subtitle “Midnight snack”: The UK’s Medicines and Healthcare products Regulatory Agency, meanwhile, has recorded 68 cases of adverse reactions to zolpidem from 2001 to 2005. (The time the drug was approved in the UK was not mentioned.)
4. True
See para.3 under the subtitle “Midnight snack”: In one case, a transatlantic flight had to be diverted after a passenger caused havoc after taking zolpidem.
5. False
See para.2 under the subtitle “Tried and tested”: He says that unlike older types of sleep medications, zolpidem does not carry as great a risk of addiction.
6. Not Given
See para.3 under the subtitle “Tried and tested”: And Wright notes that some of the reports of “sleep-driving” linked to zolpidem can be easily explained: some patients have wrongly taken the drug right before leaving work in hopes that the medicine will kick in by the time they reach home. (No patients as office workers are mentioned in the passage.)
7. C
See para.4 from the beginning: A newly published report from Australia’s Federal Health Department describes 104 cases of hallucinations and 62 cases of amnesia experienced by people taking zolpidem since marketing of the drug began there in 2000. The health department report also mentioned 16 cases of strange sleepwalking by people taking the medication.
8. B
See the sentence in para.2 under the subtitle “Hypnotic effects” (The product information for prescribers advises that psychiatric adverse effects, including hallucinations, sleepwalking and nightmares, are more likely in the elderly, and treatment should be stopped if they occur.) and the sentence in para.3 under the subtitle “Tried and tested” (Doctors “not the product information” stress that the medication should be taken just before going to bed.)
9. B
See para.5 under the subtitle “Tried and tested”: Sanofi-Aventis spokesperson Melissa Feltmann … says that “the safety profile [of zolpidem] is well established”.
10. 674,500 (times)
See para.3 from the beginning: Various forms of the drug, made by French pharmaceutical giant Sanofi-Aventis, were prescribed674,500 times in 2005 in the UK.
11. (a) benzodiazepine-like (hypnotic)
See para.1 under the subtitle “Hypnotic effects”: The drug is a benzodiazepine-like hypnotic (类苯二氮催眠药)that promotes deep sleep by interacting with brain receptors for a chemical called gamma-aminobutyric acid.
12. risky consequences
See para.3 under the subtitle “Hypnotic effects”: Patient advocacy groups … stress that strange sleepwalking and sleep-driving behaviours can have risky consequences.
13. Food & Drug (Administration)
See para.4 under the subtitle “Tried and tested”: The US Food & Drug Administration says it is continuing to "actively investigate" and collect information about cases linking zolpidem to unusual side effects.
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